Ph 101 Physicalchemistry

Nội dung text: Ph 101 Physicalchemistry

1. CH4003 Lecture Notes 1 (Erzeng Xue) PH 101 PHYSICALCHEMISTRY
2. Course General Information Lectures Tuesday 4pm Room No.: LT 7a Thursday 9am Room No.: LT 7a Lecture Notes: Available at the class and on the UL’s web ( Tutorial Friday 4pm, Room: LT 7a (to be arranged) Labs Group 2A: Monday 4-6pm, Room No: PharmLab, Group 2B: Thursday 1-3pm, Room No: PharmLab Weeks 6, 7,8,9,10 (both groups) Attendance is MANDATORY MUST have white lab coat and safety specs Assessment 60% End term Exam 40% Tests & Lab. Attendance/Reports 2
3. Lecture Notes Available at the class and on the UL’s web 3
4. PH 101 Course Outline UNIT I Intermolecular forces and states of matter; binding forces between molecules, the states of matter, the Gaseous state, the liquid state, solids and the Crystalline state,  Phase equilibrium and the phase rule. 4
5. PH 101 Course Outline UNIT II Thermodynamics: The first law of thermodynamics The second law of thermodynamics. The third law of thermodynamics,  Free energy functions and applications. Chemical kinetics and Arrhenius equation, the half life and shelf life. 5
6. PH 101 Course Outline UNIT III 6 Physical properties of Drug Molecules:  Dielectric constant Induced polarization Dipole moment Refractive Index Molar Refraction and  Optical Rotatory Dispersion 6
7. PH 101 Course Outline ❑UNIT IV Solutions: Concentration expressions, solutions of non-electrolytes, ideal and real solutions, colligative properties, molecular weight determinations. Solutions of Electrolytes: Properties of solutions of electrolytes. The Arrhenius theory of electrolyte dissociation.  The modern theory of strong electrolytes and other coefficients for expressing colligative properties. 7
8. Delivery and Assessment Mode ❑ Contact hours: 84 Lecture hours and - hours for Tutorials/Assignments - hours for Practical. ❑ Mode of assessment: Coursework 40% (At least two tests, plus assignment/quizzes/ practical) and University examination 60%. ❑ Tests schedule th th Test I - end of 6 week, Test II – end of 11 week (negotiable) 8
9. Recommended Texts ❑Prime Texts Atkins P.W., 2002, Physical Chemistry, 7th ed., Oxford University Press. Atkins P.W., 1998, Physical Chemistry, 6th ed., Oxford University Press. Other Texts Atkins P.W, 2001, The Elements of Physical Chemistry, 3rd ed., Oxford University Press. Alberty, R.A. and Silbey, R.J., 2000, Physical Chemistry, 3rd ed., Wiley. 9
10. Experiments There are 5 experiments 1. Kinetics of hydrolysis of ethyl acetate studied by conductance measurements. 2. The effect of temperature on reaction rate: Application of the Arrhenius equation to the kinetics of oxidation of iodide by persulphate. 3. Triangular phase diagram. 4. Thermodynamics. 5. Preparation of standard solutions Note: A Laboratory Manual will be available for photocopying before laboratorysessions commence in Week 3. 10